Main results from blood test at 08.00 this morning were platelets 593, up from 480 in November, and Hb 95, down from 105 in November. It looks as though Hydroxycarbamide is no lomger effective in keeping the platelets down without depressing the Hb at the same time. Dr I is referring me to Dr McL, who has more experience of myelofibrosis and who may want a bone marrow biopsy to see what's going on at that level. Dr L thought one of the JAK inhibitors may be the next move, but they too have the effect of lowering Hb. The appointment with DrMcL is at 09.40 on February 5.